Fission yeast cells divide precisely at their middle. Once the cell reaches a critical size, the scaffolding protein anillin/Mid1p accumulates at the cell’s equator, where it anchors to the plasma membrane to form “nodes”, the precursors for actomyosin contractile ring (ACR) assembly (Upper Figure 4). These nodes then coalesce and recruit the necessary contractile ring … Continue reading Story 4: How Fission Yeast Divide at Their Middle?